Annual report pursuant to Section 13 and 15(d)

Document and Entity Information

Document and Entity Information - USD ($)
12 Months Ended
Dec. 31, 2021
Mar. 09, 2022
Jun. 30, 2021
Document and Entity Information      
Document Type 10-K    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Dec. 31, 2021    
Entity File Number 001-35994    
Entity Registrant Name HEAT BIOLOGICS, INC.    
Entity Incorporation DE    
Entity Tax Identification Number 26-2844103    
Entity Address, Address Line One 627 Davis Drive, Suite 400    
Entity Address, City or Town Morrisville    
Entity Address, State or Province NC    
Entity Address, Postal Zip Code 27560    
City Area Code 919    
Local Phone Number 240-7133    
Title of 12(b) Security Common Stock, $0.0002 par value per share    
Trading Symbol HTBX    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag false    
Entity Shell Company false    
Entity Public Float     $ 169,016,850
Entity Common Stock, Shares Outstanding   25,649,824  
Entity Central Index Key 0001476963    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2021    
Document Fiscal Period Focus FY    
Amendment Flag false    
Auditor Name BDO USA, LLP    
Auditor Firm ID 243    
Auditor Location Raleigh, NC