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Publications

Pipeline

Pipeline

  • Pipeline Chart
  • Publications
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Combination Immunotherapy: T-cell costimulation (OX40L, ICOSL, and 4-1BBL) secreted locally by Gp96-Ig vaccines, elicits robust antigenspecific, memory T cell responses and tumor elimination Heat Biologics 2016

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Locally secreted Fc-OX40L is superior to systemic, antibody mediated, OX40 co-stimulation for combination immunotherapy Heat Biologics 2016

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Vector Engineered Immunotherapy Incorporating gp96-Ig and T Cell Costimulatory Fusion Proteins Elicits a Superior Antigen-Specific CD8+ T Cell Response Heat Biologics 2015

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Immunotherapy meets epigenetics: Gp96-Ig cellular vaccine genetic signature is modulated by the inhibition of histone modifications Heat Biologics 2015

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Comparative Combination Cancer Immunotherapy with Vaccination and TNFRSF Stimulation Heat Biologics 2014

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CD8 T cell response in a phase I study of therapeutic vaccination of advanced NSCLC with allogeneic tumor cells secreting endoplasmic reticulum-chaperone gp96-Ig-peptide complexes Heat Biologics 2013

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